Recent publications
For a full list of published articles visit: NCBI database. (* denotes graduate student, # undergraduate student trainee)
• Amankrah SA, Salpadoru T, #Cotton K, Patrauchan MA, Wozniak KL, Gerasimchuk N. Synthesis, Characterization and Antimicrobial Activity of Trimethylantimony(V) Biscyanoximates, a New Family of Antimicrobials. Molecules. 2024 Dec 6;29(23):5779. doi: 10.3390/molecules29235779. PMCID: PMC11643687
• Heydarian N, Ferrell M, *Nair AS, Roedl C, Peng Z, Nguyen TD, Best W, Wozniak KL, Rice CV. Low-Molecular Weight Branched Polyethylenimine Reduces Cytokine Secretion from Human Immune System Monocytes Stimulated with Bacterial and Fungal PAMPs. ChemMedChem. 2024 Aug 1;19(15):e202400011. doi: 10.1002/cmdc.202400011. Epub 2024 Jul 12. PMID: 38740551
• Salpadoru T, Pinks KE, #Lieberman JA, #Cotton K, Wozniak KL, Gerasimchuk N, Patrauchan MA. Novel antimony-based antimicrobial drug targets membranes of Gram-positive and Gram-negative bacterial pathogens. Microbiol Spectr. 2024 Jun 4;12(6):e0423423. doi: 10.1128/spectrum.04234-23. Epub 2024 Apr 23.PMID: 38651882
• Heydarian N, Ferrell M, *Nair AS, Roedl C, Peng Z, Nguyen TD, Best W, Wozniak KL, Rice CV. Neutralizing Staphylococcus aureus PAMPs that Trigger Cytokine Release from THP-1 Monocytes. ACS Omega. 2024 Feb 23;9(9):10967-10978. doi: 10.1021/acsomega.4c00043. eCollection 2024 Mar 5. PMID: 38463252
• *Conn, B.N., #Lieberman, J.A., #Chatman, P., #Cotton, K., Essandoh, M.A., Ebqa’ai, M., Nelson, T.L., Wozniak, K.L. Antifungal activity of eumelanin-inspired indoylenepheyleneethynylene against Cryptococcus neoformans. Frontiers in Microbiology. Jan 2024. DOI: 10.3389/fmicb.2023.1339303
• Alake, S.E., Ice, J., Robinson, K., Price, P., Hatter, B., Wozniak, K.L., Lin, D., Chowanadisai, W., Smith, B.J., Lucas, E.A. Reduced estrogen signaling contributes to bone loss and cardiac dysfunction in interleukin‐10 knockout mice. Physiological Reports. Dec 2023. DOI: 10.14814/phy2.15914
• Goughenour, K, A.S. Nair* (co-1st author), J. Xu, M.A. Olszewski, and K.L. Wozniak. Dendritic Cells: Multifunctional Roles in Host Defenses to Cryptococcus Infections. Journal of Fungi. Nov 2023. DOI: 10.3390/jof9111050.Invited Review.
• Alake, S.E.; Ice, J.; Adedigba, P., Hatter, B., Islam, P., Lu, P., Chandrashekar, R., Olawale, F., Orphan, J., Perez, L., Butcher, J., Wozniak, K.L., Lin, D., Chowanadisai, W., Smith, B.J., Lucas, E.A. OR10-02-23 Pinto Beans Supplementation Prevents Vascular Dysfunction in an Interleukin-10 Dependent Manner in Female Mice Fed an Atherogenic Diet. Current Developments in Nutrition. July 2023. DOI:10.1016/j.cdnut.2023.101454
• *Conn, B.N. and K.L. Wozniak. Innate Pulmonary Phagocytes and Their Interactions with Pathogenic Cryptococcus Species. Journal of Fungi. 2023 May 27;9(6):617.doi: 10.3390/jof9060617. Invited Review
• Alake, S.E., S. Lightfoot, K.L. Wozniak, D. Lin; W. Chowanadisai, B.J. Smith; E. A. Lucas. Wheat Germ Supplementation Reduces Inflammation and Gut Epithelial Barrier Dysfunction in IL-10 KO Mice Fed a Pro-atherogenic Diet. Journal of Nutrition. 2023 Jan 9;S0022-3166(23)02510-5. https://doi.org/10.1016/j.tjnut.2023.01.008
• *Nelson, B.N., #C.S. Daugherty, R.S. Sharp, J.L. Booth, V.I. Patel, J.P. Metcalf, K.L. Jones, and K.L. Wozniak. Protective Interaction of Human Phagocytic APC Subsets with Cryptococcus neoformans Induces Genes Associated with Metabolism and Antigen Presentation. Frontiers in Immunology. Nov 2022. doi: 10.3389/fimmu.2022.1054477
• Gerasimchuk, N., K. Pinks, T. Salpadoru, #K. Cotton, O. Michka, M.A. Patrauchan, and K.L. Wozniak. Non-antibiotic antimony-based antimicrobials. Molecules. 2022, 27, 7171. https://doi.org/10.3390/molecules27217171
• *Hawkins, A.N., #B.D. Determann II, *B.N. Nelson, and K.L. Wozniak. Transcriptional Changes in Pulmonary Phagocyte Subsets Dictate the Outcome Following Interaction With The Fungal Pathogen Cryptococcus neoformans. Frontiers in Immunology. 12:722500. September 2021. doi: 10.3389/fimmu.2021.722500
• *Nelson, B.N., #S.G. Beakley, #S. Posey, #B. Conn, #E. Maritz, J. Seshu, and K.L. Wozniak. Antifungal activity of dendritic cell lysosomal proteins against Cryptococcus neoformans. Scientific Reports. June 30, 2021. DOI : 10.1038/s41598-021-92991-6.
• Chen, Y., S. M. Vargas, T. C. Smith II, S. L. R. Karna, K.L. Wozniak, F. L. Wormley Jr., and J. Seshu. Borrelia peptidoglycan interacting Protein (BpiP) contributes to the fitness of Borrelia burgdorferi against host-derived factors and influences virulence in mouse models of Lyme disease. PLOS Pathogens, 2021.
• *Nelson, B.N., *A.N. Hawkins, K.L. Wozniak. Pulmonary Macrophage and Dendritic Cell Responses to Cryptococcus neoformans. Frontiers in Cellular and Infection Microbiology. Feb 11, 2020. https://doi.org/10.3389/fcimb.2020.00037. PMCID: PMC7026008. Invited Review
• Hole CR, Wager CML, Castro-Lopez N, Campuzano A, Cai H, Wozniak KL, Wang Y, Wormley FL Jr. Induction of memory-like dendritic cell responses in vivo. Nature Communications. 2019 Jul 4;10(1):2955. doi: 10.1038/s41467-019-10486-5. PubMed PMID: 31273203; PubMed Central PMCID: PMC6609631.
• Leopold Wager, C.M., C.R. Hole, A. Campuzano, N. Castro-Lopez, H. Cai, M.C. Caballero Van Dyke, K.L. Wozniak, Y. Wang, F.L. Wormley, Jr. IFN-γ Immune Priming of Macrophages In Vivo Induces Prolonged STAT1 Binding and Protection against Cryptococcus neoformans. PLOS Pathogens. Oct 10, 2018. doi.org/10.1371/journal.ppat.1007358
• K.L. Wozniak Interactions of Cryptococcus with Dendritic Cells. Journal of Fungi. 2018. 4(1), 36; doi:10.3390/jof4010036.
• Caballero Van Dyke, M.C., A.K. Chaturvedi, S.E. Hardison, C.M. Leopold Wager, N. Castro-Lopez, C.R. Hole, K.L. Wozniak, and F.L. Wormley, Jr. Induction of Broad-Spectrum Protective Immunity against Disparate Cryptococcus Serotypes. Frontiers in Immunology. 2017. doi.org/10.3389/fimmu.2017.01359
• Campuzano, A., N. Castro-Lopez, K.L. Wozniak, C.M. Leopold Wager, and F.L. Wormley, Jr. Dectin-3 is not required for protection against Cryptococcus neoformans infection. PLoS One. 2017. 12(1): e0169347. doi: 10.1371/journal.pone.0169347. PMID: 28107361
• Hole, C.R., C.M. Leopold Wager, A. Mendiola, K.L. Wozniak, A. Campuzano, X. Lin, and F.L. Wormley, Jr. Anti-fungal Activity of Plasmacytoid Dendritic Cells Against Cryptococcus neoformans In Vitro Requires Expression of Dectin-3 (CLEC4D) and Reactive Oxygen Species. Infection and Immunity. 2016; 84 (9) 2493-504. PMCID: PMC4995896.
• Leopold Wager, C.M., C.R. Hole, K.L. Wozniak, and F.L. Wormley, Jr. Cryptococcus and Innate Phagocytes: Complex Interactions that Influence Disease Outcome. Frontiers in Microbiology. 2016; 7:105. doi:10.3389/fmicb.2016.00105. PMCID: PMC4746234
• Hung, C.Y., K.L. Wozniak, and G. Cole. Flow Cytometric Analysis of Protective T-Cell Response Against Pulmonary Coccidioides Infection. 2016. Methods in Molecular Biology, Vaccine Design - Methods and Protocols: Volume 1: Vaccines for Human Diseases. Chapter 31. Humana Press.
• Zhai, B.*, K.L. Wozniak* (co-first author), J. Masso-Silva, S. Upadhyay, C.R. Hole, A. Rivera, F.L. Wormley, Jr., and X. Lin. Development of protective inflammation and cell-mediated immunity against Cryptococcus neoformans after exposure to hyphal mutants. mBio. 2015; Oct 6;6(5). pii: e01433-15. PMCID: PMC4611043
• Leopold Wager, C.M., C.R. Hole, K.L. Wozniak, M.A. Olszewski, M. Mueller, F.L. Wormley, Jr. STAT1 signaling within macrophages is required for antifungal activity against Cryptococcus neoformans. Infection and Immunity. 2015; 83 (12) 4513-27. PMCID: PMC4645398
• Wozniak, K.L., M.A. Olszewski, and F.L. Wormley, Jr. Molecules at the Interface of Cryptococcus and the Host that Determine Disease Susceptibility. Fungal Genetics and Biology. 2015; 78:87-92. PMID: 25445308
• Leopold Wager, C.M., C.R. Hole, K.L. Wozniak, M.A. Olszewski, F.L. Wormley, Jr. STAT1 Signaling is Essential for Protection against Cryptococcus neoformans Infection in Mice. The Journal of Immunology. 2014; 193(8): 4060-71. PMID: 25200956
• Chaturvedi, A.K., R.S. Hameed, K.L. Wozniak, C.R. Hole, C.M. Leopold Wager, S.T. Weintraub, J.L. Lopez-Ribot, and F.L. Wormley, Jr. Vaccine-mediated Immune Responses to Experimental Pulmonary Cryptococcus gattii Infection in Mice. PLoS One. 2014; 13;9(8):e104316. PMID: 25119981
• Wozniak, K.L., C.R. Hole, J. Yano, P.L. Fidel, Jr., and F.L. Wormley, Jr. Characterization of IL-22 and Antimicrobial Peptide Production in Mice Protected Against Pulmonary Cryptococcus neoformans Infection. Microbiology. 2014; 160 (Pt 7): 1440-52. PMID: 24760968
• Wozniak, K.L., J.K. Kolls, and F.L. Wormley, Jr. Depletion of Neutrophils in a Protective Model of Pulmonary Cryptococcosis Results in Increased IL-17A Production by Gamma/delta T cells. BMC Immunology. 2012;13:65. PMCID:PMC3538069.
• Hole, C.R., H. Bui, F.L. Wormley, Jr., and K.L. Wozniak. Mechanisms of Dendritic Cell Lysosomal Killing of Cryptococcus. Scientific Reports. 2012;2:739. PMCID: PMC3472389.
• Hardison S.E., G. Herrera, M.L. Young, C.R. Hole, K.L. Wozniak, F.L. Wormley, Jr. Protective immunity against pulmonary cryptococcosis is associated with STAT1-mediated classical macrophage activation. The Journal of Immunology. 2012;189:4060-8. PMCID: PMC3466339.
• Yano, J., J.K. Kolls, K.I. Happel, F.L. Wormley, K.L. Wozniak, P.L. Fidel. The acute neutrophil response mediated by S100 alarmins during vaginal Candida infections is independent of the Th17-pathway. PLoS One. 2012;7(9):e46311. PMCID: PMC3457984.
• Wozniak, K.L., M.A. Olszewski, and F.L. Wormley, Jr. Host Immune Responses Against Pulmonary Fungal Pathogens. Pulmonary Infections. 2012; pp 85-128. Amer Amal (Ed.), InTech.
• Wozniak, K.L., S.E. Hardison, M.A. Olszewski, and F.L. Wormley Jr. Induction of Protective Immunity Against Cryptococcosis. Mycopathologia. 2012; 173: 387-94. PMID: 22143898.
• Wozniak, K.L., M.L. Young, and F.L.Wormley, Jr. Protective Immunity Against Experimental Pulmonary Cryptococcosis in T Cell Depleted Mice. Clinical Vaccine Immunology. 2011; 18:717-23. PMCID: PMC3122518.
• Wozniak, K.L., S.E. Hardison, J.K. Kolls, and F.L. Wormley, Jr. Role of IL-17A on Resolution of Pulmonary C. neoformans Infection. PLoS ONE. 2011; 6: e17204. PMCID: PMC3040760.
• Wozniak, K.L. and S.M. Levitz. T Cell and Dendritic Cell Immune Responses to Cryptococcus. Cryptococcus: From human pathogen to model yeast. 2011; pp 387-396. ASM Press.